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Metastatic clearcellrenalcellcancer has traditionally been treated with cytokines (interferon or interleukin-2).
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Currently there is no curative treatment for metastatic clearcellrenalcellcancer, the commonest variant of the disease.
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The patient had undergone a right radical nephrectomy for stage II clearcellcarcinomaofthekidney 6 years previously.
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During the past decade, researchers have identified the von Hippel-Lindau (VHL) gene as an important tumor suppressor in clearcellcarcinomaofthekidney.
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The predominant clear squamous neoplastic cells had foci of granular eosinophilic cytoplasm and resembled conventionalrenalcellcarcinoma.
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A previously unreported feature is the occurrence of a conventionalrenalcellcarcinoma component in one of our cases.
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These findings led to the diagnosis of simultaneous double primary clearcellcarcinomasofkidney and liver.
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A total of 133 patients with early renalclearcellcarcinoma (T1-2N0M0) with surgical indications were continuously selected.